Protein-based fluorescent metal nanoclusters for small molecular drug screening.
نویسندگان
چکیده
A facile drug screening method based on synthesis of fluorescent gold nanoclusters inside albumin proteins loaded with small molecular drugs and comparing the relative fluorescence intensities of the resultant gold nanoclusters has been developed and successfully applied for the quantitative measurement of drug-protein binding constants.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 89 شماره
صفحات -
تاریخ انتشار 2014